XpressGT®: Revolutionizing
Biomarker Quantification
Simple, scalable, and cost-effective 2-hydroxybutyrate measurement.
Why 2-Hydroxybutyrate (2-HB) Matters
Discover the Power of 2-Hydroxybutyrate (2-HB) for Diabetes Screening
2-Hydroxybutyrate (2-HB), also known as alpha-hydroxybutyrate, is a key biomarker with significant relevance in diabetes care. Elevated 2-HB levels are strongly associated with insulin resistance (IR) and impaired glucose tolerance (IGT), key indicators of type 2 diabetes development. XpressGT® aims to provide a more effective solution for the early detection of diabetes and gestational diabetes, enabling timely intervention and better management of these conditions.
Complexity and Costs
The Challenge with Current Methods
Currently, three methods are available for the quantification of 2-hydroxybutyrate: LC-MS, GC-MS, and NMR. These methods are costly, hard to set up, and thus only available in specialized labs or core facilities. Large datasets cannot be measured, which is essential for biomarker discovery and validation.
Fasting Requirements
Poor Repeatability
Unpleasant Experience
Higher Labor Costs
Duration: 2-3 h
False Positive Results
Streamlining Biomarker Analysis
XpressGT® Kit (RUO): Reliable 2-HB Detection Made Easy
The XpressGT® Kit is a research-use-only (RUO) solution for precise measurement of 2-hydroxybutyrate (2-HB) levels in serum and plasma samples. Designed for high-throughput labs, this enzymatic assay kit offers fast, accurate results, making it an ideal choice for studies related to insulin resistance, prediabetes, and gestational diabetes.
Simplifying 2-Hydroxybutyrate Quantification
Why choose XpressGT®
Elevate your research capabilities with the XpressGT® Kit’s proven performance and easy integration into existing lab workflows. Ideal for researchers seeking a scalable, interference-free approach to studying 2-HB levels. Key Benefits are:
Achieve consistent and reliable results with less than 3.5% variability within assays and less than 5% variability across multiple assays.
Validated for use on popular automated analyzers, including ABBOTT Alinity c and ROCHE Cobas, and adaptable for other platforms.
Includes all necessary reagents, calibration standards, and controls to streamline setup and ensure precise measurement across a range of 20-400 µM 2-HB.
A Superior Alternative
XpressGT® vs. Oral Glucose Tolerance Test (OGTT)
The OGTT is an established diagnostic procedure for diabetes testing, known for its high sensitivity. However, it is unpopular due to its cost and complexity, leading to the underestimation of diabetes and delayed treatment. XpressGT® offers a novel enzymatic test with a colorimetric readout that provides results in just 8 minutes, making it a practical and efficient alternative.
Results in 8 min
Fits Routine Blood Draws
Interference Resistance
Clinical Analyzer Compatible
Serum and Plasma Validated
Patent Protected
Get Started Today
Ready to Transform Your Lab?
Discover how XpressGT® can revolutionize your biomarker analysis.
Contact us for more information and to place your order.
Insuline Resistance
α-Hydroxybutyrate Is an Early Biomarker of Insulin Resistance and Glucose Intolerance in a Nondiabetic Population
Early Metabolic Markers of the Development of Dysglycemia and Type 2 Diabetes and Their Physiological Significance
Impaired glucose
α-Hydroxybutyric Acid Is a Selective Metabolite Biomarker of Impaired Glucose Tolerance
Gestational diabetes
Metabolomic and genetic architecture of gestational diabetes subtypes
Gas Chromatography–Mass Spectroscopy-Based Metabolomics Analysis Reveals Potential Biochemical Markers for Diagnosis of Gestational Diabetes Mellitus
GLP-1 analoga monitoring
Effects of Tirzepatide, a Dual GIP and GLP-1 RA, on Lipid and Metabolite Profiles in Subjects With Type 2 Diabetes
Endometriosis
A comprehensive multiplatform metabolomic analysis reveals alterations of 2-hydroxybutyric acid among women with deep endometriosis related to the pesticide trans-nonachlor
Liver disease
Hepatic NADH reductive stress underlies common variation in metabolic traits
